| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Phospho-ERK1 (T202/Y204) + ERK2 (T185/Y187) Rabbit pAb | BKM-00108 | 100 μL |
Product Information
Description | Phospho-ERK1 (T202/Y204) + ERK2 (T185/Y187) rabbit polyclonal antibody |
Protein full name | Mitogen-activated protein kinase 1 |
Synonyms | APK1, ERK, ERK-1, ERK-2, ERK1, ERK2, ERT1, MAPK1,MAPK3, P42MAPK, P44MAPK, PRKM1, PRKM2, p44, p42, p44-MAPK, p42-MAPK, P-ERK, P-ERK1/2, P-ERK1, P-ERK2 |
Immunogen | KLH conjugated Synthetic phosphopeptide corresponding to Human ERK1 (T202/Y204) + ERK2 (T185/Y187) |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 43 kDa |
Uniprot ID | P63085, P63086 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 400-1: 800 | lung, kidney |
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Images
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Western blot analysis of ERK1 (T202/Y204) + ERK2 (T185/Y187) (GB11004) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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