| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -5HT1A Receptor Rabbit pAb | BKM-00204 | 100 μL |
Product Information
Description | 5HT1A Receptor rabbit polyclonal antibody |
Protein full name | 5-hydroxytryptamine receptor 1A |
Synonyms | 5-HT-1A, G-21, Serotonin receptor 1A, HTR1A, ADRB2RL1, ADRBRL1 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse 5HT1A Receptor |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID | P08908 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, CACO-2, Raji, HepG2, HCT116 |
Background
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Images
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Western blot analysis of 5-HT1A (GB111060) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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