| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -CD81 Rabbit pAb | BKM-00213 | 100 μL |
Product Information
Description | CD81 rabbit polyclonal antibody |
Protein full name | CD81 antigen |
Synonyms | 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, CD81, Tapa1 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD81 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 30 kDa |
Uniprot ID | P60033, P35762, Q62745 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skeletal muscle |
Background
CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 appears to promote muscle cell fusion and support myotube maintenance. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
Images
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Western blot analysis of CD81 (GB111073) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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