| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -beta 2 Microglobulin Rabbit pAb | BKM-00261 | 100 μL |
Product Information
Description | beta 2 Microglobulin rabbit polyclonal antibody |
Protein full name | Beta-2-microglobulin |
Synonyms | Beta-2-microglobulin form pI 5.3, B2M, CDABP0092, HDCMA22P |
Immunogen | Recombinant protein corresponding to Mouse beta 2 Microglobulin |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 14 kDa |
Observed MW. | 14 kDa |
Uniprot ID | P61769 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, HepG2, Raji |
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Images
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Western blot analysis of β2-Microglobulin (GB111119) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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