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Anti -AMF Rabbit pAb
BKM-00292
百科盟

产品信息

产品名称 产品编号 规格
Anti -AMF Rabbit pAb BKM-00292 100 μL

产品简介

Product Information



Description

AMF rabbit polyclonal antibody

Protein full name

Glucose-6-phosphate isomerase

Synonyms

GPI, Autocrine motility factor, AMF, NLK, Neuroleukin, Phosphoglucose isomerase, PGI, PHI, Gpi1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse AMF

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted, Cytoplasm

Uniprot ID

P06745, Q6P6V0





Applications



Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 1500

brain, spinal cord, spleen





Background


This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.




Images


Picture 1.png

Immunohistochemistry analysis of paraffin-embedded mouse Immune spleen using AMF (GB111160) at dilution of 1: 1000

Picture 2.png

Immunohistochemistry of paraffin embedded mouse spinal cord using GPI (GB111160) at dilution of 1:500 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded mouse spleen using GPI (GB111160) at dilution of 1:500 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded rat brain using GPI (GB111160) at dilution of 1:500 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded rat spleen using GPI (GB111160) at dilution of 1:500 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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