| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Cullin 7 Rabbit pAb | BKM-00578 | 50 μL |
Product Information
Description | Cullin 7 rabbit polyclonal antibody |
Protein full name | Cullin-7 |
Synonyms | Cul7, CUL7, 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7 |
Immunogen | Recombinant protein corresponding to Mouse Cullin 7 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 192 kDa |
Observed MW. | 180 kDa |
Uniprot ID | Q14999, Q8VE73 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, testis |
Background
Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.
Images
 |
Western blot analysis of Cul7 (GB111493) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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