| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -EGFR Rabbit pAb | BKM-00587 | 100 μL |
Product Information
Description | EGFR rabbit polyclonal |
Protein full name | Epidermal growth factor receptor |
Synonyms | EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human EGFR |
Isotype | IgG |
Subcellular location | Cytoplasm, Nucleus, Cell membrane, Secreted |
Predicted MW. | 134 kDa |
Observed MW. | 175 kDa |
Purity | Affinity purification |
Uniprot ID | P00533 |
Applications
applications | species | dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HeLa, A549, HepG2, A431, H1299, MCF7 |
IHC | Human | 1: 500-1: 1000 | esophageal cancer |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
 |
Western blot analysis of EGFR (GB111505) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: A549 cell lysate Lane 3: HepG2 cell lysate Lane 4: A431 cell lysate Lane 5: H1299 cell lysate Lane 6: MCF7 cell lysate |
 |
Immunofluorescent analysis of paraformaldehyde-fixed human esophageal cancer using EGFR (GB111505) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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