| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -CD73 Rabbit pAb | BKM-00867 | 100 μL |
Product Information
Description | CD73 rabbit polyclonal |
Protein full name | 5'-nucleotidase |
Synonyms | 5'-NT, CD73, Nt5e, Nt5, Nte, 5' nucleotidase precursor, E5NT, Ecto-5'-nucleotidase |
Immunogen | Recombinant protein corresponding to Mouse CD73 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 64 kDa |
Observed MW. | 64 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney, retina |
Background
CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts.
Images
| Western blot analysis of CD73 (GB111807) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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