| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Bad Rabbit pAb | BKM-01029 | 100 μL |
Product Information
Description | Bad rabbit polyclonal antibody |
Protein full name | Bcl2-associated agonist of cell death |
Synonyms | BAD, BBC2, BBC6, BCL2L8, Bcl-XL/Bcl-2-Associated Death Promoter |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bad |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Mitochondrion outer membrane, Cytoplasm |
Uniprot ID | Q61337, Q92934, O35147 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 600 | brain, lung, spleen |
Background
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Images
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Immunohistochemistry of paraffin embedded rat brain using BAD (GB11198) at dilution of 1:300 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using BAD (GB11198) at dilution of 1:300 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using BAD (GB11198) at dilution of 1:300 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using BAD (GB11198) at dilution of 1:300 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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