| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Properdin/PFC Rabbit pAb | BKM-01092 | 50 μL |
Product Information
Description | Properdin/PFC rabbit polyclonal antibody |
Protein full name | Properdin |
Synonyms | Complement factor P, Cfp, Pfc, BFD, Properdin P factor complement |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Properdin |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 50 kDa |
Observed MW. | 53 kDa |
Uniprot ID | P11680 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | serum |
Background
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
Images
| Western blot analysis of Properdin (GB112049) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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