| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -ADIPOR1 Rabbit pAb | BKM-01280 | 100 μL |
Product Information
Description | ADIPOR1 rabbit polyclonal antibody |
Protein full name | Adiponectin receptor protein 1 |
Synonyms | Progestin and adipoQ receptor family member 1, Adipor1, Parq1, TESBP1A |
Immunogen | Recombinant protein corresponding to Mouse ADIPOR1 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cell membrane |
Uniprot ID | Q91VH1 |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC/IF | Mouse, Rat | 1:600-1:1200 | rectum |
Background
Acrp30 is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes. This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR- .
Images
| Immunohistochemistry of paraffin embedded mouse rectum using Adipor1 (GB112269) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat rectum using Adipor1 (GB112269) at dilution of 1:600 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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