| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -c-Myb Rabbit pAb | BKM-01318 | 100 μL |
Product Information
Description | c-Myb rabbit polyclonal antibody |
Protein full name | Transcriptional activator Myb |
Synonyms | Proto-oncogene c-Myb, Myb, MYB proto-oncogene transcription factor, v-myb avian myeloblastosis viral oncogene homolog, Cmyb |
Immunogen | Recombinant protein corresponding to Mouse c-Myb |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 71 kDa |
Observed MW. | 80 kDa |
Uniprot ID | P10242, P06876 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, kidney, colon |
Background
The MYB protein is a transcription factor that plays a key role in regulating the proliferation/differentiation of progenitor cells in bone marrow, colonic crypts, and neurogenic niches . It is involved in the regulation of epithelial-to-mesenchymal transition (EMT) and invasion in neuroblastoma, colon carcinoma, and embryonic kidney cells through the upregulation of the transcription repressor Slug . It also a DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3', and plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Images
| Western blot analysis of cMYB (GB112317) at dilution of 1: 500 |
| Western blot analysis of cMYB (GB112317) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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