| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Cardiac Troponin I Rabbit pAb | BKM-01401 | 50 μL |
Product Information
Protein full name | Cardiac Troponin I |
Synonyms | Cardiac troponin I, TNNI3, TNNC1, cTnI, CMH7, cardiac muscle, TNNI3, Troponin I type 3 cardiac , cardiac type, CTnI |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human Cardiac Troponin I |
Uniprot ID | P19429 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Cytoplasm, Cytoskeleton |
Predicted MW. / Observed MW. | 24 kDa / 28 kDa |
Applications
WB | Mouse, Rat | 1: 250-1: 500 | heart |
IHC/IF | Mouse, Rat | 1: 100-1: 400 | heart, myocardial infarction |
Background
Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Images
| Western blot analysis of cTnI (GB112408) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded mouse heart using CTNI (GB112408) at dilution of 1: 200 |
| Immunohistochemistry analysis of paraffin embedded rat myocardial infarction using CTNI (GB112408) at dilution of 1: 200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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