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Anti -DNA Polymerase beta Rabbit pAb
BKM-01429
百科盟

产品信息

产品名称 产品编号 规格
Anti -DNA Polymerase beta Rabbit pAb BKM-01429 50 μL

产品简介

Product Information


Description

DNA Polymerase beta rabbit polyclonal antibody

Protein full name

DNA polymerase beta

Synonyms

POLB, DNA pol beta, DNA directed DNA polymerase beta

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse DNA Polymerase beta

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q8K409, P06766




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 400-1: 4000

brain, kidney, lung, ovary, testis




Background


Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse brain using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded mouse ovary using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 3.png

Immunohistochemistry analysis of paraffin-embedded mouse ovary using 

POLB (GB112436) at dilution of 1: 4000

Picture 4.png

Immunohistochemistry of paraffin embedded mouse testis using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded rat brain using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 6.png

Immunohistochemistry of paraffin embedded rat kidney using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 7.png

Immunohistochemistry of paraffin embedded rat lung using POLB (GB112436) at dilution of 1:1000 (400x lens)

Picture 8.png

Immunofluorescence of paraffin embedded mouse brain using POLB (GB112436) at dilution of 1:300 (400x lens)

Picture 9.png

Immunofluorescence of paraffin embedded mouse ovary using POLB (GB112436) at dilution of 1:300 (400x lens)

Picture 10.png

Immunofluorescence of paraffin embedded rat kidney using POLB (GB112436) at dilution of 1:300 (400x lens)

Picture 11.png

Immunofluorescence of paraffin embedded rat testis using POLB (GB112436) at dilution of 1:300 (400x lens)




Storage


StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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