| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -CCR3 Rabbit pAb | BKM-01447 | 50 μL |
Product Information
Description | CCR3 rabbit polyclonal antibody |
Protein full name | Probable C-C chemokine receptor type 3 |
Synonyms | C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Macrophage inflammatory protein 1-alpha receptor-like 2, IP-1 alpha RL2, CD193, Ccr3, Cmkbr1l2, Cmkbr3 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CCR3 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 50 kDa |
Uniprot ID | P51678 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse | 1: 300-1: 600 | liver |
Background
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21.
Images
 | Western blot analysis of CCR3 (GB112453) at dilution of 1: 300 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
扫码关注 更多精彩
在线客服
