| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -BMP2 Rabbit pAb | BKM-01516 | 100 μL |
Product Information
Description | BMP2 rabbit polyclonal antibody |
Protein full name | Bone morphogenetic protein 2 |
Synonyms | BMP2, BDA2, BMP2A, bone morphogenetic protein 2 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse BMP2 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted |
Predicted MW. | 45 kDa |
Observed MW. | 45 kDa |
Uniprot ID | P12643, P21274, P49001 |
Applications
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, spleen, lung |
IHC/IF | Human (predicted), Mouse, Rat | 1: 200-1: 1000 | bone |
Background
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
Images
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WB analysis of BMP2 (GB11252). |
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IHC analysis of BMP2 (GB11252). |
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IHC analysis of BMP2 (GB11252). |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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