| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -IKB beta Rabbit pAb | BKM-01921 | 100 μL |
Product Information
Description | IKB beta rabbit polyclonal |
Protein full name | NF-kappa-B inhibitor beta |
Synonyms | NFKBIB, IKBB, IkB-beta, IkappaBbeta, TRIP9, NFKB inhibitor beta |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse IKBβ |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human, Mouse, Rat | 1:300-1:600 | lung, kidney, colon, liver, testis |
IF | Human, Mouse, Rat | 1:300-1:600 | lung, kidney, colon, liver, testis |
Background
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Images
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using IKBβ (GB11306) at dilution of 1: 300 |
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Immunohistochemistry analysis of paraffin-embedded human colon using IKBβ (GB11306) at dilution of 1: 300 |
 |
Immunohistochemistry analysis of paraffin-embedded mouse lung using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded rat liver using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded rat testis using IKBβ (GB11306) at dilution of 1: 300 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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