| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -EDD Rabbit pAb | BKM-02188 | 50 μL |
Product Information
Description | EDD rabbit polyclonal |
Protein full name | E3 ubiquitin-protein ligase UBR5 |
Synonyms | DD5, EDD, EDD1, FLJ11310, hHYD, HYD, KIAA0896, Progestin induced protein, UBR5, Rat100, Ubiquitin protein ligase |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse EDD |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Mouse, Rat | 1: 350-1: 700 | spleen |
Background
UBR5, also named as ubiquitin protein ligase E3 component n-reconin5, is a HECT domain-containing protein as a myocardin-binding protein. UBR5 is highly conserved in metazoans, has unique structural features, and has been implicated in regulation of DNA damage response, metabolism, transcription, and apoptosis. Hence, UBR5 is a key regulator of cell signaling relevant to broad areas of cancer biology . The human UBR5 gene has 59 exons, encoding an approximately 10kb mRNA and >300 kDa protein with widespread expression in various cell types.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using EDD (GB113338) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin-embedded rat spleen using EDD (GB113338) at dilution of 1: 700 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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