| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Activin Receptor Type IA Rabbit pAb | BKM-02243 | 50 μL |
Product Information
Description | Activin Receptor Type IA rabbit polyclonal |
Protein full name | Activin receptor type-1 |
Synonyms | Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type-1, Activin receptor-like kinase 2, ACTR-I, ACTRI, Acvr1, ACVRLK2, FOP, TSRI, SKR1, ALK2, Hydroxyalkyl protein kinase |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Acvr1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | heart, liver |
Background
ACVR1 (activin receptor type I), also known as ALK2 or ACTRI, is a receptor for activin. It forms a stable complex with type II receptor after ligand binding. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. ACVR1 is expressed in many tissues including skeletal muscle and chondrocytes. It functions as a receptor for bone morphogenetic protein (BMP) and induces Indian hedgehog in chondrocytes during skeletal development.
Images
 | Western blot analysis of Acvr1 (GB113399) at dilution of 1: 1500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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