| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -COMMD1/MURR1 Rabbit pAb | BKM-02288 | 100 μL |
Product Information
Description | COMMD1/MURR1 rabbit polyclonal |
Protein full name | COMM domain-containing protein 1 |
Synonyms | C2orf5, COMMD1, MURR1, Protein Murr1, Copper metabolism gene MURR1 |
Immunogen | Recombinant protein corresponding to Mouse COMMD1/MURR1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 21 kDa |
Observed MW. | 21 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse | 1: 500-1: 1500 | liver, prostate, uterine |
Background
COMMD1(COMM domain-containing protein 1), also named MURR1, is implicated in copper homeostasis by binding one copper ion per monomer. COMMD1 was reported to accelerate the ubiquitination and degradation of NF-kappa-B subunits, its deficiency exerts enhanced NF-kappa-B mediated celluar response. Ubiquitinated by XIAP (X-linked inhibitor of apoptosis), COMMD1 undergoes proteasomal degradation. SOD1 activity can be downregulated by COMMD1.
Images
 | Western blot analysis of COMMD1 (GB113448) at dilution of 1: 1500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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