| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Actin Regulatory Protein CAPG/MCP Rabbit pAb | BKM-02435 | 100 μL |
Product Information
Description | Actin Regulatory Protein CAPG/MCP rabbit polyclonal |
Protein full name | Macrophage-capping protein |
Synonyms | Actin regulatory protein CAP-G, AFCP, CAPG, MCP, Myc basic motif homolog 1, Mbh1, Actin-capping protein GCAP39, Gelsolin like capping protein, HEL S 66 |
Immunogen | Recombinant protein corresponding to Mouse MCP |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Predicted MW. | 39 kDa |
Observed MW. | 39 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | lung, spleen, kidney |
IHC | Mouse | 1: 2000-1: 4000 | lung |
Background
CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.
Images
| Western blot analysis of MCP (GB113610) at dilution of 1: 1500 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung using MCP (GB113610) at dilution of 1: 4000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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