| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -CoREST Rabbit pAb | BKM-02456 | 50 μL |
Product Information
Description | CoREST rabbit polyclonal |
Protein full name | REST corepressor 1 |
Synonyms | COREST, KIAA0071, Protein CoREST, RCOR, RCOR1, RCOR1Specific, Protein CoREST |
Immunogen | Recombinant protein corresponding to Mouse CoREST |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 53 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis, brain, lung |
Background
RCOR1, also named as REST corepressor 1, is a 485 amino acid protein, which belongs to the CoREST family. RCOR1 is a essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. The calculated molecular weight of RCOR1 is a 53 kDa, but the phosphorylated RCOR1 is about 60-65 kDa.
Images
 | Western blot analysis of CoREST (GB113633) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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