| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -ERK2 Rabbit pAb | BKM-02523 | 100 μL |
Product Information
Description | ERK2 rabbit polyclonal antibody |
Protein full name | Mitogen-activated protein kinase 1 |
Synonyms | MAPK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, mitogen-activated protein kinase 1 |
Immunogen | Recombinant protein corresponding to Mouse ERK2 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 42 kDa |
Uniprot ID | P63085, P28482, P63086 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, spleen, brain |
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known asextracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylatesnuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Images
|
Western blot analysis of ERK2 (GB11370) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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