| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Factor B Rabbit pAb | BKM-02636 | 100 μL |
Product Information
Description | Factor B rabbit polyclonal antibody |
Protein full name | Complement factor B |
Synonyms | BF, BFD, C3/C5 convertase, CFAB, CFB, FB, FBI12, GBG, Glycine rich beta glycoprotein, H2 Bf, PBF2, Properdin factor B |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Factor B |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 85 kDa |
Observed MW. | 85 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney, prostate |
Background
Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is a 93-100 kDa glycoprotein and is cleaved into Ba (33 kDa) and Bb (60 kDa) by factor D in the presence of C3b . The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This antibody raised against 573-761aa of human complement factor B can recognize complement factor B and Bb fragment.
Images
 | Western blot analysis of Factor B (GB113815) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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