| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -DKK2 Rabbit pAb | BKM-02648 | 50 μL |
Product Information
Description | DKK2 rabbit polyclonal antibody |
Protein full name | Dickkopf-related protein 2 |
Synonyms | Dickkopf-2, Dickkopf related protein 2, DKK-2, DKK2, hDkk 2, mDkk-2 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse DKK2 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 28 kDa |
Observed MW. | 28 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 1000-1: 2000 | kidney, heart, lung |
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Images
 | Western blot analysis of DKK2 (GB113829) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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