| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -ADRA1B Rabbit pAb | BKM-02674 | 100 μL |
Product Information
Description | ADRA1B rabbit polyclonal antibody |
Protein full name | Alpha-1B adrenergic receptor |
Synonyms | ADRA1, ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, ALPHA1BAR |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ADRA1B |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1200 | colon cancer, ovarian cancer, kidney, spleen, testis, brain |
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Images
 | Immunohistochemistry analysis of paraffin-embedded human colon cancer using ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded human ovarian cancerusing ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded mouse kidney using ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded mouse spleen using ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded rat testis using ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using ADRA1B (GB113857) at dilution of 1: 1200 |
 | Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using ADRA1B (GB113857) at dilution of 1: 1200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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