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Anti -CCR5 Rabbit pAb
BKM-03676
百科盟

产品信息

产品名称 产品编号 规格
Anti -CCR5 Rabbit pAb BKM-03676 50 μL

产品简介

Product Information


Description

CCR5 rabbit polyclonal

Protein full name

C-C chemokine receptor type 5

Synonyms

CC-CKR-5,CCCKR5,CCR-5,CD195,CKR-5,CKR5,CMKBR5,IDDM22,C-C motif chemokine receptor 5

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CCR5

Isotype

IgG

Purity

Affinity purification

Predicted MW.

41KDa

Observed MW.

41KDa

Subcellular location

Cell membrane

Uniprot ID

P51682



Applications


applications

species

dilution

Positive tissue

WB

Mouse, Rat

1:500-1:1000

Inflammatory spleen,

Inflammatory liver, thymus

IHC

Mouse, Rat

1:500-1:1000

lymph node

IF

Mouse, Rat

1:500-1:1000

ovary, lung, inflammatory liver, immune spleen



Background


C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific tissue and organ targets. Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells. Certain individuals carry a mutation known as CCR5-Δ32 in the CCR5 gene, protecting them against these strains of HIV.




Images



Western blot analysis of CCR5 (GB11504) at dilution of 1:800.

Line 1:Mouse Inflammatory spleen tissue lysate

Line 2:Mouse Inflammatory liver tissue lysate

Line 3:Mouse thymus tissue lysate

Line 4:Rat Inflammatory spleen tissue lysate

Line 5:Rat Inflammatory liver tissue lysate

Line 6:Rat thymus tissue lysate


Immunohistochemistry analysis of paraffin-embedded human lymph node using CCR5 (GB11504) at dilution of 1:500


Immunohistochemistry analysis of paraffin-embedded human lymph node using CCR5 (GB11504) at dilution of 1:500


Immunofluorescent analysis of paraformaldehyde-fixed mouse ovary using CCR5 (GB11504) at dilution of 1:500

Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using CCR5 (GB11504) at dilution of 1:500

Immunofluorescent analysis of paraformaldehyde-fixed mouse inflammatory liver using CCR5 (GB11504) at dilution of 1:500
Immunofluorescent analysis of paraformaldehyde-fixed rat immune spleen using CCR5 (GB11504) at dilution of 1:500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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