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Anti -CCR5 Rabbit pAb
BKM-03686
百科盟

产品信息

产品名称 产品编号 规格
Anti -CCR5 Rabbit pAb BKM-03686 100 μL

产品简介

Product Information


Description

CCR5 rabbit polyclonal antibody

Protein full name

C-C chemokine receptor type 5

Synonyms

CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22, C-C motif chemokine receptor 5

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CCR5

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

P51682, P51681, O08556




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 1000

lung, spleen, thymus




Background


C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific tissue and organ targets. Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells. Certain individuals carry a mutation known as CCR5-Δ32 in the CCR5 gene, protecting them against these strains of HIV.




Images



Picture 1.png

Immunohistochemistry of paraffin embedded mouse spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded rat spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens)

Picture 3.png

Immunofluorescence of paraffin embedded mouse spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens)

Picture 4.png

Immunofluorescence of paraffin embedded mouse thymus using CCR5 (GB11505) at dilution of 1:500 (400x lens)

Picture 5.png

Immunofluorescence of paraffin embedded rat lung using CCR5 (GB11505) at dilution of 1:500 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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