| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Endothelin 1 Rabbit pAb | BKM-04150 | 50 μL |
Product Information
Description | Endothelin 1 rabbit polyclonal antibody |
Protein full name | Endothelin-1 |
Synonyms | EDN1, ARCND3, ET1, ET-1, HDLCQ7, PPET1, QME, Endothelin 1 |
Immunogen | Recombinant protein corresponding to Mouse Endothelin 1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID | P22387 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse | 1: 500-1: 1000 | liver, lung, kiney |
Background
Endothelin 1 (ET-1), also known as preproendothelin-1 (PPET1), is a potent vasoconstrictor that in humans is encoded by the EDN1 gene and produced by vascular endothelial cells. The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. Endothelin 1 is one of three isoforms of human endothelin.
Preproendothelin is precursor of the peptide ET-1. Endothelial cells convert preproendothelin to proendothelin and subsequently to mature endothelin, which the cells release.
Images
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Western blot analysis of Endothelin1 (GB11557) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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