| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -IL-17A Receptor Rabbit pAb | BKM-04286 | 100 μL |
Product Information
Description | IL-17A Receptor rabbit polyclonal antibody |
Protein full name | Interleukin-17 receptor A |
Synonyms | IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A, IMD51 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human IL-17A Receptor |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 96 kDa |
Observed MW. | 110 kDa |
Uniprot ID | Q96F46 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, HTP-1, A20 |
Background
Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Images
 |
Western blot analysis of IL-17Ra (GB11586) at dilution of 1: 500 |
Storage
| Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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