| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Crk p38 Rabbit pAb | BKM-04341 | 50 μL |
Product Information
Description | Crk p38 rabbit polyclonal antibody |
Protein full name | Adapter molecule crk |
Synonyms | CRK, Crk p38, CRK isoform 2, CrkII; CRKII; p38, Proto oncogene C crk, v crk sarcoma virus CT10 oncogene homolog, Adapter molecule crk, Avian sarcoma virus CT10 |
Immunogen | Recombinant protein corresponding to Human Adapter molecule crk |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 34 kDa |
Observed MW. | 38 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | HepG2, A549, MCF7, 293T, U87 |
Background
Adapter molecule crk also known as proto-oncogene c-Crk or p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
Images
 |
Western blot analysis of crk (GB11645) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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