| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -PRAK Rabbit pAb | BKM-04413 | 100 μL |
Product Information
Description | PRAK rabbit polyclonal antibody |
Protein full name | MAP kinase-activated protein kinase 5 |
Synonyms | Mapkapk5, PRAK, MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK, mitogen-activated protein kinase-activated protein kinase 5 |
Immunogen | Recombinant protein corresponding to Mouse PRAK |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus |
Uniprot ID | Q8IW41, O54992 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | brain, kidney, liver cancer, lung |
Background
MAP kinase-activated protein kinase 5 is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately-spliced transcript variants of this gene encoding distinct isoforms have been reported.
Images
 | Immunohistochemistry of paraffin embedded human liver cancer using MAPKAPK-5 (GB11721) at dilution of 1:800 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using MAPKAPK-5 (GB11721) at dilution of 1:800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using MAPKAPK-5 (GB11721) at dilution of 1:800 (400x lens) |
 | Immunofluorescence of paraffin embedded human lung using MAPKAPK-5 (GB11721) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded mouse brain using MAPKAPK-5 (GB11721) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded rat kidney using MAPKAPK-5 (GB11721) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded rat lung using MAPKAPK-5 (GB11721) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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