| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -Aldolase C Rabbit pAb | BKM-04504 | 100 μL |
Product Information
Description | Aldolase C rabbit polyclonal antibody |
Protein full name | Fructose-bisphosphate aldolase C |
Synonyms | Aldoc, ALDOC, ALDC, Aldolase C, Aldolase, Fructose-bisphosphate C |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Aldolase C |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 40 kDa |
Uniprot ID | P09972, P05063, P09117 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus, cerebellum |
Background
ALDOC is one of the three aldolase isozymes (A, B, and C), encoded by three different genes. Aldolase C (fructose bisphosphate aldolase) is a key enzyme in the fourth step of glycolysis, as well as in the reverse pathway gluconeogenesis. It catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate (G3P), or glyceraldehyde, and dihydroxyacetone phosphate (DHAP) by aldol cleavage. As a result, it is a crucial player in ATP biosynthesis. In addition, ALDOC participates in the stress-response pathway for lung epithelial cell function during hypoxia and in the resistance of cerebellar Purkinje cells against excitotoxic insult.
Images
 |
Western blot analysis of ALDC (GB11825) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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