| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -KSR1 Rabbit pAb | BKM-04548 | 50 μL |
Product Information
Description | KSR1 rabbit polyclonal antibody |
Protein full name | Kinase suppressor of Ras 1 |
Synonyms | mKSR1, Protein Hb, Ksr1, Ksr, BKSR1, EK31, RSU2, SR31, Suppressor of Ras1 31 |
Immunogen | Recombinant protein corresponding to Mouse KSR1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 97 kDa |
Observed MW. | 97 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | Hek293, HeLa, U251 |
Background
KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.
Images
 |
Western blot analysis of ksr (GB11878) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
扫码关注 更多精彩
在线客服
