| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -ATG4A Rabbit pAb | BKM-04558 | 100 μL |
Product Information
Description | ATG4A rabbit polyclonal antibody |
Protein full name | Cysteine protease ATG4A |
Synonyms | Atg4a, ATG4A, APG4A, AUTL2, Autophagy related 4A cysteine peptidase |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ATG4A |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 45 kDa |
Observed MW. | 48 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, pancreas, liver |
Background
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Images
 |
Western blot analysis of ATG4 (GB11889) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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