| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -ADRM1/ARM-1 Rabbit pAb | BKM-04610 | 100 μL |
Product Information
Description | ADRM1 rabbit polyclonal |
Protein full name | Proteasomal ubiquitin receptor ADRM1 |
Synonyms | 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog, Adrm1, M(r) 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Rpn13 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ADRM1 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Mouse, Rat | 1: 500-1: 2000 | brain, hippocampus, testis, ovary |
IF | Mouse, Rat | 1: 250-1: 500 | brain, hippocampus, testis, ovary |
Background
ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.
Images
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Immunohistochemistry analysis of paraffin-embedded neonatal mice brain using ADRM1 (GB11947) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat hippocampus using ADRM1 (GB11947) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat testis using ADRM1 (GB11947) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat ovary using ADRM1 (GB11947) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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