| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti -c-Myc Rabbit pAb | BKM-04866 | 50 μL |
Product Information
| Description | c-Myc rabbit polyclonal |
| Protein full name |
Myc proto-oncogene protein |
|
Synonyms |
Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39 |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to human Myc |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Nucleus |
| Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human, Mouse, Rat | 1:100-1:200 | Liver cancer, breast cancer,lung |
Background
C-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function.
Images
 |
Immunohistochemistry analysis of paraffin-embedded human liver cancer using c-Myc (GB13076) at dilution of 1:100 |
 |
Immunohistochemistry analysis of paraffin-embedded human breast cancer using c-Myc (GB13076) at dilution of 1:100 |
 |
Immunohistochemistry analysis of paraffin-embedded mouse lung using c-Myc (GB13076) at dilution of 1:100 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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