| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti-iNOS Mouse mAb | BKM-04811 | 100 μL |
Product Information
Protein full name | Nitric oxide synthase, inducible |
Synonyms | HEP NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, INOS, NOS, NOS type II, NOS2A, NOS2, Nitric oxide synthase 2, Hepatocyte NOS, Inducible NO synthase, Inducible NOS |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse iNOS |
Uniprot ID | P35228 |
Isotype | IgG2b,k |
Purity | Affinity purification |
Predicted MW. / Observed MW. | 131 kDa / 131 kDa |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse | 1: 500-1: 1000 | Raw264.7 |
Background
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM.
Images
| WB analysis of iNOS (GB123965). |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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