| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti-Phospho-CREB (S133) Rabbit pAb | BKM-03386 | 100 μL |
Product Information
Protein full name | Cyclic AMP-responsive element-binding protein 1 |
Synonyms | CREB-1, CAMP-responsive element-binding protein 1, CAMP responsive element binding protein 1, Active transcription factor CREB, P-CREB |
Immunogen | KLH conjugated Synthetic phosphopeptide corresponding to Human CREB（S133） |
Uniprot ID | P16220 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus |
Predicted MW. / Observed MW. | 37 kDa / 43 kDa |
Applications
WB | Mouse, Rat | 1: 300-1: 600 | NIH/3T3, C6 |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
| Western blot analysis of P-CREB (GB114684) at dilution of 1: 300 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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