| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Anti-MLH1 Mouse mAb | BKM-04759 | 100 μL |
Product Information
Protein full name | DNA mismatch repair protein Mlh1 |
Synonyms | MutL protein homolog 1, COCA2, FCC2, hMLH1, HNPCC, HNPCC2, MLH1 |
Immunogen | Recombinant protein corresponding to MLH1 |
Uniprot ID | P40692 |
Isotype | IgG1,κ |
Purity | Affinity purification |
Predicted MW. / Observed MW. | 85 KDa / 85 KDa |
Applications
WB | Human | 1: 500-1: 1000 | HeLa,Jurkat,MCF7 |
Background
Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.
Images
| WB analysis of MLH1 (GB121958). |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
扫码关注 更多精彩
在线客服
