| 产品名称 | 产品编号 | 规格 |
|---|---|---|
| Recombinant Anti-Cytokeratin 17 antibody (Mouse mAb) | BKM-05107 | 100 μL |
Product Information
Protein full name | Keratin, type I cytoskeletal 17 |
Synonyms | Cytokeratin-17, CK-17, Keratin-17, Krt1-17, Krt17, K17, keratin 17 epitope S1, PCHC1, PC2 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human Cytokeratin 17 |
Uniprot ID | Q9QWL7 |
Isotype | IgG1 |
Purity | Affinity purification |
Subcellular location | Cytoplasm |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Applications
WB | Human | 1: 500-1: 2000 | Hela, HaCaT, A431 |
IHC/IF | Human | 1: 500-1: 1000 | esophageal carcinoma, Laryngeal squamous cell carcinoma |
Background
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair.Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state.Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway.
Images
| WB analysis of Cytokeratin 17(GB15363). |
| IHC analysis of Cytokeratin 17(GB15363). |
| IHC analysis of Cytokeratin 17(GB15363). |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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